The PTG-S5 automated powder flow analyzer is used to measure the flow behavior of granules and powders in compliance with the EP <2.9.36>, EP <2.9.16>, USP <1174> Pharmacopoeia and ISO 4324 standards. This instrument determines the powder flow time, the powder cone angle of the collected powder mound, the weight, the density and the volume of the powder cone. Furthermore, the EP “flowability” result is calculated by measuring the flow time of 100g of sample through a specified pouring nozzle.

Advantages:
>> Reduce process costs
>> Improve product consistency from batch to batch
>> Keep tight control of component powders, especially if they are natural products
>> Compare sources of powdered products
>> Provides an easy method to achieve quality control on bulk incoming component products
>> Provides an easy method for the control of dry and wet mixing, tableting, granulating, and capsule filling
>> Predict powder transport through conveyors, air lifts and in silos
>> Predict powder suitability for capsule and bottle filling
>> Predict product settling during transport, so called classification
>> Predict powder influence on tablet hardness and solid dosage form stability
>> Predict powder influence on tablet disintegration and friability
>> Integrated clear view dust protection dust protection hood

The PTG-NIR automatic powder and granule analysis system combines the Pharma Test PTG-S5 powder flow testing instrument with an integrated J&M TIDAS L NIR diode array spectrometer. The system is controlled by the powerful TIDASDAQ3 software including a customized script for the PTG-NIR. The system is ideal to examine the flow characteristics of a powder or granule. This combination is ideal for simultaneous detection of chemical, physical and morphological information. This information is describing the flow behaviors of a powder or granule. Other forms of solids are possible to be tested too. All the results are presented in a single report generated by the included TIDASDAQ3 software.

Advantages:
>> Measure the flow behavior of powders and granules to reduce process costs and maintain quality and consistency of the final product
>> Gather chemical, physical and morphological information by using the integrated NIR spectrometer
>> Fast diode array NIR spectrometer provides immediate full spectra and contains no moving parts
>> Excellent S/N ratio to detect weak signals
>> IQ/OQ documents included free of charge

The PT-TD300 is used to test the tapped (or “tamped”) density and apparent density of powders, granules, pigments and similar products in compliance with the current USP <616> methods 1 and methods 2 as well as with EP <2.9.34>, DIN EN ISO 787-11, ASTM B527 and ASTM D7481.18. The instrument automatically calculates the tapped density, Hausner flowability ratio and Carr compressibility index after each test and documents the results via the integrated protocol printer.

Advantages:
>> Use a single instrument to test tapped density and apparent density according to both method 1 and method 2 from USP <616>
>> Automated detection of correct cylinder position according to selected method
>> Integrated protocol printer reduces bench space requirements
>> Detailed result report including calculation of Hausner flowability ratio and Carr compressibility index
>> Evaluation of the results according to Hausner and Carr compressibility indices
>> Determine the sample weight to automatically calculate apparent and tapped density
>> Programmable qualification interval timer reminds the user to perform instrument calibration
>> Dedicated calibration programs including reports for tap number, tap height, tap frequency, weight measurement and timer function
>> Copy methods between instruments by using a common USB flash drive
>> Export test reports as text files
>> IQ/OQ documents included free of charge

The PT-SV100 Scott Volumeter determines bulk density of powders according to the following standard Monographs: USP <616>, Method II bulk density and tapped density of powders, EP <2.9.34.1>, DIN ISO 3923-2 (metallic powders): determination of apparent density and optional ASTM B329 standard test method for apparent density of metal powders and compounds.

Advantages:
>> Easy to use
>> Solid design including vibration free baseplate
>> Integrated spirit gauge to check levelness of the instrument