Nano-500 is an advanced model of micro UV VIS spectrophotometer based on Nano-300, with full range of wavelength (200-800 nm). It is with an added new function of bacterium cell concentration measurement (OD600) in a cuvette. The Nano-500 only requires 0.5-2 μl sample to measure nucleic acids, proteins as quickly as Nano-300. Nano-500 come with a 7 inch touch screen and integrated Android operating system, with no computer required. It is an ideal equipment for a biology laboratory to make life science research more efficient.